Which medication is contraindicated during pregnancy for managing migraines due to risk of fetal harm?

During pregnancy, particular attention must be given to medication safety due to the potential risks to fetal development. Ibuprofen is classified as a nonsteroidal anti-inflammatory drug (NSAID). Its use, especially in the third trimester, has been linked to serious complications, such as premature closure of the ductus arteriosus, a crucial blood vessel in fetal circulation. Furthermore, NSAIDs are associated with an increased risk of fetal renal dysfunction and decreased amniotic fluid levels, which can lead to further complications.

While acetaminophen is generally considered safer and is often the preferred analgesic during pregnancy, both ibuprofen and aspirin carry more significant risks. Aspirin, similar to ibuprofen, may increase the risk of bleeding and complications during labor and delivery and can also affect fetal development in certain circumstances.

Given these risks, particularly the strong contraindication associated with ibuprofen, this medication is typically advised against for managing migraines in pregnant individuals to safeguard fetal health.