Which condition is not a contraindication for the administration of magnesium sulfate?

The administration of magnesium sulfate is primarily indicated for conditions like preterm labor or severe preeclampsia and can be influenced by various patient-specific factors. Hyperkalemia, or elevated levels of potassium, is not considered a contraindication for magnesium sulfate administration. In fact, magnesium sulfate can sometimes be safely used in patients with hyperkalemia because it can help to stabilize cardiac membranes and reduce the risk of cardiac complications associated with high serum potassium levels.

On the other hand, the other conditions listed—hypocalcemia, renal failure, and myasthenia gravis—are contraindications. Hypocalcemia could lead to an increased risk of magnesium toxicity as magnesium can affect calcium levels in the body. In patients with renal failure, the kidneys may not effectively excrete magnesium, heightening the risk of hypermagnesemia. Myasthenia gravis, an autoimmune neuromuscular disorder, can be exacerbated by magnesium sulfate because magnesium can interfere with neuromuscular transmission and worsen muscle weakness.

Thus, the correct choice highlights that while caution is warranted in specific circumstances, hyperkalemia itself does not serve as a barrier to the safe use of magnesium sulfate in patients.