In patients with chronic hypertension, elevated uric acid levels ranging from which values may indicate risk for superimposed preeclampsia?

In patients with chronic hypertension, elevated uric acid levels are significant because they can serve as a biochemical marker indicating the risk for superimposed preeclampsia. The correct range of 4.5 to 6.0 mg/dl is clinically relevant, as this level has been linked to an increased likelihood of developing this serious condition.

Preeclampsia is characterized by hypertension and often accompanied by other systemic bodily changes, and uric acid levels serve as a marker for the placental function and overall maternal-fetal well-being. When uric acid levels rise within this specific range, it may reflect increased oxidative stress and impaired renal function, both of which are associated with the pathophysiology of preeclampsia.

While lower or higher ranges may not provide the same predictive value for superimposed preeclampsia, understanding the critical threshold of 4.5 to 6.0 mg/dl helps in identifying patients who may require closer monitoring and intervention. This range is therefore crucial for clinical decision-making related to the management of women with chronic hypertension during pregnancy.